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Development of nanostructured bone substitutes and study of immunological aspects in bone tissue regeneration
Project/agreement No.
6.2.-25/2016/0175
Project funding
149 988.73 EUR, including 75 000.00 EUR RSU funding and 74988.73 EUR RTU funding
Project manager
Dr.med. Jeļena Eglīte, Jānis Ločs (RTU)
Project realization
15.02.2016. - 28.02.2019.
Aim
Research objectives: develop synthesis technology for amorphous calcium phosphate nanoparticles (with surface area exceeding 150 m2/g) and production method of nanostructured ceramic aggregates, produce calcium phosphate ceramic aggregates with the sizes from 0.3 to 1.4 mm and surface area exceeding 50 m2/g
The project aims at developing two innovative technologies
1. The technology related to the development of implantable material production technology that could be applied in dentistry and plastic surgery
2. The diagnostic complex aimed at detecting immunogenetic markers prior to implant use in patients which will allow the developing of the method for patient-specific implantable material selection
The project aims at developing two innovative technologies
1. The technology related to the development of implantable material production technology that could be applied in dentistry and plastic surgery
2. The diagnostic complex aimed at detecting immunogenetic markers prior to implant use in patients which will allow the developing of the method for patient-specific implantable material selection
Description
Rīga Stradiņš University and Riga Technical University carry out a scientific cooperation project during the period from February 2016 to February 2019 aimed at establishing inter-university research teams, conducting interdisciplinary and competitive studies
Partner RTU
Faculty of Material Science and Applied Chemistry, Institute of General Chemical Engineering (IGCEI) and Rudolfs Cimdins Riga Biomaterials Innovation and Development Centre (RBIDC)
Partner RSU
RSU Joint Laboratory of Clinical Immunology and Immunogenetics
Activities of the project
- Development of nanostructured calcium phosphate granule production technology (RTU)
- In vitro and in vivo experiments (RTU + RSU)
- Fundamental studies and development of marker identification protocols (RSU)
- Development of a multiplex immunodetection method (RSU + RTU)
- Communication with potential project partners, attending conferences and meetings (RTU + RSU)
Project results
- 4 scientific publications have been published
- International project applications EuroNanoMed, M.ERA-NET, HIVERA, and 2 project applications Horizon 2020 have been submitted within the project
