Biology and Genetics

Study Course Description

Course Description Statuss:Approved

Course Description Version:7.00

Study Course Accepted:06.08.2024 13:17:55

Study Course Information
Course Code:		BUMK_055		LQF level:		Level 6
Credit Points:		2.00		ECTS:		3.00
Branch of Science:		Biology		Target Audience:		Social Welfare and Social Work; Psychology
Study Course Supervisor
Course Supervisor:		Agrita Puzuka
Study Course Implementer
Structural Unit:		Department of Biology and Microbiology
The Head of Structural Unit:
Contacts:		Riga, 16 Dzirciema Street, bmkrsu[pnkts]lv, +371 67061584
Study Course Planning
Full-Time - Semester No.1
Lectures (count)		12	Lecture Length (academic hours)		2	Total Contact Hours of Lectures		24
Classes (count)		4	Class Length (academic hours)		2	Total Contact Hours of Classes		8
Total Contact Hours								32
Part-Time - Semester No.1
Lectures (count)		6	Lecture Length (academic hours)		2	Total Contact Hours of Lectures		12
Classes (count)		2	Class Length (academic hours)		2	Total Contact Hours of Classes		4
Total Contact Hours								16
Study course description
Preliminary Knowledge:
Biology, chemistry at secondary school level.
Objective:
Acquire knowledge of the biological processes in an organism to understand the maintenance of human health and development of diseases, as well as to obtain necessary skills in order to use this knowledge in practice.
Topic Layout (Full-Time)
No.	Topic			Type of Implementation		Number	Venue
1	The subject of the human biology. Life, the diversity of its forms. Prokaryotes. Eukaryotes.			Lectures		1.00	E-Studies platform
2	Eukaryotic cell. Plasma membrane; structure, functions, pathology.			Lectures		1.00	E-Studies platform
3	Eukaryotic cell cytoplasm; structure, functions, pathology.			Lectures		1.00	E-Studies platform
4	The nucleus of a cell. Chromatin, its types. The chromosomes. Human karyotype.			Lectures		1.00	E-Studies platform
5	Basis of molecular biology. Structure of DNA. Replication. Gene expression. Transcription. Translation.			Lectures		1.00	E-Studies platform
6	Cell cycle. Types of cell division. Mitosis. Meiosis. Atypical cell division. Cell division defects and human pathology.			Lectures		1.00	E-Studies platform
7	Gametogenesis. Oogenesis. Spermatogenesis. Gamete anomalies. Biological basis of fertilisation.			Lectures		1.00	E-Studies platform
8	Genetics. Mendel’s laws. Mono-, di, polyhybrid cross. Test-cross.			Lectures		1.00	E-Studies platform
9	Gene interaction. Types of interactions between allelic and non-allelic genes. Gene linkage. Chromosomal theory of heredity.			Lectures		1.00	E-Studies platform
10	Types of inheritance. Autosomal; X and Y chromosome-linked and multifactorial types of inheritance.			Lectures		1.00	E-Studies platform
11	Variability, its types. Alterations on genes, chromosomes, genomes.			Lectures		1.00	E-Studies platform
12	Chromosomal disorders.			Lectures		1.00	E-Studies platform
13	Cell structure and cell types (microscopic slides). Implementation of the protocol.			Classes		1.00	E-Studies platform
14	Mitosis in animal and plant cells (analysis of microscopic slides and schemes). Gametogenesis; germ cell morphology (analysis of microscopic slides and schemes).			Classes		1.00	E-Studies platform
15	Solving genetic problems.			Classes		1.00	E-Studies platform
16	Family tree construction and analysis. Case study of chromosomal diseases.			Classes		1.00	E-Studies platform
Topic Layout (Part-Time)
No.	Topic			Type of Implementation		Number	Venue
1	The subject of the human biology. Life, the diversity of its forms. Prokaryotes. Eukaryotes.			Lectures		0.50	E-Studies platform
2	Eukaryotic cell. Plasma membrane; structure, functions, pathology.			Lectures		0.50	E-Studies platform
3	Eukaryotic cell cytoplasm; structure, functions, pathology.			Lectures		0.50	E-Studies platform
4	The nucleus of a cell. Chromatin, its types. The chromosomes. Human karyotype.			Lectures		0.50	E-Studies platform
5	Basis of molecular biology. Structure of DNA. Replication. Gene expression. Transcription. Translation.			Lectures		0.50	E-Studies platform
6	Cell cycle. Types of cell division. Mitosis. Meiosis. Atypical cell division. Cell division defects and human pathology.			Lectures		0.50	E-Studies platform
7	Gametogenesis. Oogenesis. Spermatogenesis. Gamete anomalies. Biological basis of fertilisation.			Lectures		0.50	E-Studies platform
8	Genetics. Mendel’s laws. Mono-, di, polyhybrid cross. Test-cross.			Lectures		0.50	E-Studies platform
9	Gene interaction. Types of interactions between allelic and non-allelic genes. Gene linkage. Chromosomal theory of heredity.			Lectures		0.50	E-Studies platform
10	Types of inheritance. Autosomal; X and Y chromosome-linked and multifactorial types of inheritance.			Lectures		0.50	E-Studies platform
11	Variability, its types. Alterations on genes, chromosomes, genomes.			Lectures		0.50	E-Studies platform
12	Chromosomal disorders.			Lectures		0.50	E-Studies platform
13	Cell structure and cell types (microscopic slides). Implementation of the protocol.			Classes		0.50	E-Studies platform
14	Mitosis in animal and plant cells (analysis of microscopic slides and schemes). Gametogenesis; germ cell morphology (analysis of microscopic slides and schemes).			Classes		0.50	E-Studies platform
15	Solving genetic problems.			Classes		0.50	E-Studies platform
16	Family tree construction and analysis. Case study of chromosomal diseases.			Classes		0.50	E-Studies platform
Assessment
Unaided Work:
On the basis of certain pre-defined criteria, individual work on "My family tree" should be prepared and presented in the lesson. Using knowledge on chromosomal diseases, students should be able to analyse the case reports of a chromosomal disease and present their observations in the lesson.
Assessment Criteria:
After every two lectures, students must complete an e-test on the topics covered. The test must be completed within a certain time and will be assessed with a mark. Also the practical class protocols will be evaluated. A total of 8 evaluations in the course. If an e-test or e-protocol is not submitted within the deadline, it is evaluated as fail. The course final grade will be formed from average mark of the e-tests and e-protocols. If the student has not completed/ participated in 25% of the course activities (tests and protocols), then the exam evaluation criteria described above are no longer valid and the oral exam must be taken.
Final Examination (Full-Time):		Exam (Written)
Final Examination (Part-Time):		Exam (Written)
Learning Outcomes
Knowledge:		Upon completion of the course, students will have acquired basic knowledge of cellular and genetic processes in the human and genesis of pathologies.
Skills:		Upon completion of the course, students will learn the skill to analyze microphotograph images of cells and describe observations and will be able to solve simple tasks in genetics.
Competencies:		Upon completion of the course, students will be able to analyse cases in medical genetics. They will evaluate the role of organoids in functioning of tissues, organs and the body.
Bibliography
No.	Reference
Required Reading
1	Lekciju materiāls (e-studijās)
2	A. Krūmiņa, V. Baumanis. - Eikariotu šūnu bioloģija, RSU, Rīga, 2015
3	Turnpenny P.D., & Ellard S., Emery's Elements of Medical Genetics, 15th edition, Elsevier, 2017
Additional Reading
1	Balodis V Ģ u.c., Rokasgrāmata bioloģijā, Zvaigzne ABC, 2015
Other Information Sources
1	National Center for Biotechnology Information Search database. Available from: www.ncbi.nlm.nih.gov
2	The New England Journal of Medicine (NEJM)
3	S. Madera. - Bioloģija. I, II un III daļa, R, Zvaigzne ABC, 2001