Pharmaceutical Pharmacology

Study Course Description

Course Description Statuss:Approved

Course Description Version:1.00

Study Course Accepted:21.03.2024 13:19:54

Study Course Information
Course Code:		FKK_049		LQF level:		Level 7
Credit Points:		7.33		ECTS:		11.00
Branch of Science:		Basic Sciences of Medicine, including Pharmacy; Pharmacology		Target Audience:		Pharmacy
Study Course Supervisor
Course Supervisor:		Inga Urtāne
Study Course Implementer
Structural Unit:		Department of Pharmaceutical Chemistry
The Head of Structural Unit:
Contacts:		Riga, 16 Dzirciema Street, Block A, 5th floor, Room No 502, farmkkrsu[pnkts]lv, +371 67061544
Study Course Planning
Full-Time - Semester No.1
Lectures (count)		2	Lecture Length (academic hours)		2	Total Contact Hours of Lectures		4
Classes (count)		9	Class Length (academic hours)		4	Total Contact Hours of Classes		36
Total Contact Hours								40
Full-Time - Semester No.2
Lectures (count)		3	Lecture Length (academic hours)		2	Total Contact Hours of Lectures		6
Classes (count)		14	Class Length (academic hours)		3	Total Contact Hours of Classes		42
Total Contact Hours								48
Part-Time - Semester No.1
Lectures (count)		10	Lecture Length (academic hours)		4	Total Contact Hours of Lectures		40
Classes (count)		10	Class Length (academic hours)		4	Total Contact Hours of Classes		40
Total Contact Hours								80
Study course description
Preliminary Knowledge:
Physiology, biochemistry, anatomy, microbiology, chemistry.
Objective:
To promote the acquisition of knowledge about the main pharmacological groups of drugs, their mechanism of action and their use. Promote understanding of the action of the drug in the human body, its effects on receptors, pharmacokinetics, pharmacodynamics, interactions and side effects.
Topic Layout (Full-Time)
No.	Topic			Type of Implementation		Number	Venue
1	General pharmacology. Basic principles of the recipe. Introduction to Pharmacokinetics and Pharmacodynamics. Drug interactions and side effects.			Lectures		1.00	auditorium
2	Basic principles of searching for evidence-based and other pharmacological information			Lectures		1.00	auditorium
3	Drug polymorphism. Therapeutic drug monitoring.			Lectures		1.00	auditorium
4	Antibacterial resistance, biosimilars			Lectures		1.00	auditorium
5	Toxicology. Pharmacology of special patient groups: pregnant women, children.			Lectures		1.00	auditorium
6	Autonomous System: Drugs that affect cholinoreceptors.			Classes		1.00	laboratory
7	Autonomous system: Drugs that affect adrenoreceptors.			Classes		1.00	laboratory
8	Histamine receptor antagonists. Local anesthetics. Laboratory work - anaphylactic shock.			Classes		1.00	laboratory
9	Colloquium			Classes		1.00	laboratory
10	Cardiovascular drugs: antihypertensive drugs. Laboratory work - hypertensive crisis.			Classes		1.00	laboratory
11	Cardiovascular system drugs: lipid lowering agents, diuretics			Classes		1.00	laboratory
12	Cardiovascular system drugs: drugs affecting the blood coagulation system and antiarrhythmics.			Classes		1.00	laboratory
13	Colloquium			Classes		1.00	laboratory
14	Pharmacology of endocrine system			Classes		1.00	laboratory
15	Pharmacology of analgesics (NSAIDs), glucocorticoids			Classes		1.00	laboratory
16	Biological medicines. Characteristics of products used in chemotherapy.			Classes		0.50	laboratory
17	Immunopharmacology			Classes		0.50	laboratory
18	Colloquium			Classes		1.00	laboratory
19	Drugs that act in CNS – benzodiazepines, antiepileptics, antiparkinsonian drugs, sleep aids			Classes		0.50	laboratory
20	Drugs that act in CNS – psychotropic, neuroleptic drugs			Classes		0.50	laboratory
21	Drugs that act in CNS – antidepressants, muscle relaxants, nootropics			Classes		1.00	laboratory
22	Central analgesics (narcotic, non-narcotic), migraine therapy			Classes		1.00	laboratory
23	Colloquium			Classes		1.00	laboratory
24	Pharmacology of respiratory system			Classes		1.00	laboratory
25	Agents affecting the gastrointestinal tract			Classes		1.00	laboratory
26	Renal and urinary system pharmacology			Classes		1.00	laboratory
27	Colloquium			Classes		1.00	laboratory
28	Antibiotics – beta-lactam antibiotics (penicillins, cephalosporins, carbapenems, monobactams), macrolides, tetracyclines, aminoglycosides. Basic principles of antibiotic use. Antiseptics and antimicrobials			Classes		1.00	laboratory
29	Antibacterials – quinolones, nitrofuran derivatives, anti-tuberculosis, antimalarials, HIV therapy			Classes		1.00	laboratory
30	Colloquium			Classes		1.00	laboratory
Topic Layout (Part-Time)
No.	Topic			Type of Implementation		Number	Venue
1	General pharmacology. Basic principles of the recipe. Introduction to Pharmacokinetics and Pharmacodynamics. Drug interactions and side effects.			Lectures		0.50	auditorium
2	Basic principles of searching for evidence-based and other pharmacological information			Lectures		0.50	auditorium
3	Drug polymorphism. Therapeutic drug monitoring.			Lectures		1.00	auditorium
4	Antibacterial resistance, biosimilars			Lectures		1.00	auditorium
5	Toxicology. Pharmacology of special patient groups: pregnant women, children.			Lectures		1.00	auditorium
6	Autonomous System: Drugs that affect cholinoreceptors.			Classes		0.50	laboratory
7	Autonomous system: Drugs that affect adrenoreceptors.			Classes		0.50	laboratory
8	Histamine receptor antagonists. Local anesthetics. Laboratory work - anaphylactic shock.			Classes		0.25	laboratory
9	Colloquium			Classes		0.50	laboratory
10	Cardiovascular drugs: antihypertensive drugs. Laboratory work - hypertensive crisis.			Lectures		0.50	auditorium
				Classes		0.75	laboratory
11	Cardiovascular system drugs: lipid lowering agents, diuretics			Lectures		0.50	auditorium
				Classes		0.50	laboratory
12	Cardiovascular system drugs: drugs affecting the blood coagulation system and antiarrhythmics.			Lectures		0.50	auditorium
				Classes		0.50	laboratory
13	Colloquium			Classes		0.50	laboratory
14	Pharmacology of endocrine system			Lectures		0.50	auditorium
				Classes		0.50	laboratory
15	Pharmacology of analgesics (NSAIDs), glucocorticoids			Lectures		0.50	auditorium
				Classes		0.25	laboratory
16	Biological medicines. Characteristics of products used in chemotherapy.			Classes		0.25	laboratory
17	Immunopharmacology			Classes		0.25	auditorium
18	Colloquium			Classes		0.50	laboratory
19	Drugs that act in CNS – benzodiazepines, antiepileptics, antiparkinsonian drugs, sleep aids			Lectures		0.50	auditorium
				Classes		0.50	laboratory
20	Drugs that act in CNS – psychotropic, neuroleptic drugs			Classes		0.50	laboratory
21	Drugs that act in CNS – antidepressants, muscle relaxants, nootropics			Classes		0.50	laboratory
22	Central analgesics (narcotic, non-narcotic), migraine therapy			Lectures		0.50	auditorium
23	Colloquium			Classes		0.50	laboratory
24	Pharmacology of respiratory system			Lectures		0.50	auditorium
				Classes		0.25	laboratory
25	Agents affecting the gastrointestinal tract			Lectures		0.50	auditorium
				Classes		0.25	laboratory
26	Renal and urinary system pharmacology			Lectures		0.50	auditorium
27	Colloquium			Classes		0.50	laboratory
28	Antibiotics – beta-lactam antibiotics (penicillins, cephalosporins, carbapenems, monobactams), macrolides, tetracyclines, aminoglycosides. Basic principles of antibiotic use. Antiseptics and antimicrobials			Lectures		0.50	auditorium
				Classes		0.25
29	Antibacterials – quinolones, nitrofuran derivatives, anti-tuberculosis, antimalarials, HIV therapy			Lectures		0.50	auditorium
				Classes		0.50	laboratory
30	Colloquium			Classes		0.50	laboratory
Assessment
Unaided Work:
Individual and group work by analysing the mechanism of action and clinical cases of the drug. It is recommended to fill in the study course survey, evaluating the existing course content and creating proposals for updating the course.
Assessment Criteria:
The final grade of the study course consists of the average mark of the colloquium (50%) and the mark of the exam (50%).
Final Examination (Full-Time):		Exam
Final Examination (Part-Time):		Exam
Learning Outcomes
Knowledge:		As a result of successful study course students will be able: 1. To recognise and identify drugs by their pharmacological group. 2. To evaluate the basic principles of prescribing. 3. To identify pharmacokinetic and pharmacodynamic differences between drugs. 4. To identify the most important indications, contraindications, side effects and risks of the drug, interactions.
Skills:		As a result of successful completion of the study course students will have skills in: 1. Prescribing according to the requirements of the Cabinet of Ministers regulations. 2. Collecting and systematising drug substances based on pharmacological groups. 3. Choosing and applying the most appropriate medicines for specific clinical situations. 4. Evaluating possible side effects, interactions and risks of the drug in appropriate clinical situations.
Competencies:		Successful completion of the course will enable students to: 1. Use the acquired knowledge to provide pharmaceutical care in different patient and disease groups. 2. Analyse and evaluate the effect of medicine on the human body. 3. Select and analyse information about medicines, their use during the treatment process.
Bibliography
No.	Reference
Required Reading
1	Stringer J.L. (Ed.). (2022). Basic Concepts in Pharmacology: What You Need to Know for Each Drug Class, 6th ed. McGraw Hill.
2	Preface. Katzung B.G., & Kruidering-Hall M, et.al. (Eds.), (2021). Katzung & Trevor's Pharmacology: Examination & Board Review, 13th ed. McGraw Hill.
3	Curry, Stephen H. Introduction to drug disposition and pharmacokinetics / Stephen H. Curry, Robin Whelpton. Chichester, West Sussex: Wiley, 2017. xi, 323 lpp. (brošēts).
Additional Reading
1	Lilley, Linda Lane. Pharmacology and the Nursing Process / Linda Lane Lilley, RN, PhD, Shelly Rainforth Collins, et.al. 9th ed. St. Louis, Missouri: Elsevier, 2020 xviii, 932, [2] lpp.
2	Ciccone, Charles D. Pharmacology in rehabilitation. Philadelphia: F.A. Davis, 2022. xxvii, 706 lpp. Contemporary perspectives in rehabilitation
3	Brunton, L. L., Chabner, B. A., Knollmann, B. C. Goodman & Gilman's The Pharmacological Basis of Therapeutics. 12th ed. McGraw-Hill Companies, 2018
4	Ritter, J. M., Lewis, L. D., Mant, T. G., Ferro, A. A. Textbook of Clincal Pharmacology and Therapeutics. 5th ed. Hodden Education. 2008, p.465
5	Raffa, R. B., Rawls, S. M., Beyzarov, E. P. Netter's Illustrated Pharmacology. Icon Learning systems. 2013, p.411
Other Information Sources
1	DynaMed Plus
2	RSU abonētās zinātniskās datubāzes