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Clinical Pharmacology, Pharmacotherapy, Toxicology
Study Course Description
Course Description Statuss:Approved
Course Description Version:8.00
Study Course Accepted:11.03.2021 10:02:07
| Study Course Information | |||||||||
| Course Code: | FLK_046 | LQF level: | Level 7 | ||||||
| Credit Points: | 2.00 | ECTS: | 3.00 | ||||||
| Branch of Science: | Clinical Medicine | Target Audience: | Pharmacy; Clinical Pharmacy | ||||||
| Study Course Supervisor | |||||||||
| Course Supervisor: | Mārcis Zeibārts | ||||||||
| Study Course Implementer | |||||||||
| Structural Unit: | Department of Pharmacology | ||||||||
| The Head of Structural Unit: | |||||||||
| Contacts: | Riga, Konsula street 21, 1st floor; Marcis[pnkts]Zeibarts rsu[pnkts]lv; Indra[pnkts]Dumbergarsu[pnkts]lv; +371 67613517 | ||||||||
| Study Course Planning | |||||||||
| Full-Time - Semester No.1 | |||||||||
| Lectures (count) | 5 | Lecture Length (academic hours) | 2 | Total Contact Hours of Lectures | 10 | ||||
| Classes (count) | 7 | Class Length (academic hours) | 3 | Total Contact Hours of Classes | 21 | ||||
| Total Contact Hours | 31 | ||||||||
| Study course description | |||||||||
| Preliminary Knowledge: | Anatomy, physiology, pathology, biochemistry, basics of pharmacology, clinical medicine. | ||||||||
| Objective: | To provide knowledge of specific pharmacotherapy in accordance with the pathology of the organ systems studied during the study course. To gain knowledge of the effect of therapeutic drugs on disease mechanisms and pathogenesis. The aim is to achieve that students are able to apply their knowledge of the mechanisms of action of drug substances and to integrate pharmacotherapeutic strategies in the treatment of a given case, to anticipate the course of events resulting from the treatment. Students should understand the mechanisms, indications and contraindications, adverse side effects, interactions, toxicity, and focus on the pharmacokinetic properties of each product. | ||||||||
| Topic Layout (Full-Time) | |||||||||
| No. | Topic | Type of Implementation | Number | Venue | |||||
| 1 | Cardiology. CHD. Hypertension | Classes | 1.00 | E-Studies platform | |||||
| 2 | Cardiology. Chronic heart failure. Arrhytmias. | Classes | 1.00 | E-Studies platform | |||||
| 3 | Pharmacological treatment of arrhythmias. Prevention of thromboembolic events. Pharmacotherapy of inflammatory heart diseases (endocarditis – infectious and rheumatic; pericarditis). | Lectures | 1.00 | E-Studies platform | |||||
| 4 | Pulmonology. Asthma. COPD. Pneumonia | Classes | 1.00 | E-Studies platform | |||||
| 5 | Clinical pharmacology of agents affecting gastrointestinal system. Pharmacotherapy for increased gastric secretion, peptic ulcer, Gastroesophageal reflux disease (GERD). Pharmacotherapy for gastrointestinal system. | Lectures | 1.00 | E-Studies platform | |||||
| 6 | Clinical pharmacology of agents that affect renal function. Pharmacotherapy of main syndromes of kidney damage (nephritic syndrome, nephrotic syndrome). Acute urinary tract infection (cystitis, pyelonephritis, acute urethral syndrome), treatment tactics. Chronic renal disease, pharmacotherapy. | Lectures | 1.00 | E-Studies platform | |||||
| 7 | Hypothalamic and pituitary hormone preparations. Clinical pharmacology of medication affecting thyroid gland and parathyroid. Clinical pharmacology of medicines affecting bone mineralization. Vitamin preparations. Clinical pharmacology of drugs used in the treatment of diabetes mellitus. Principles of insulin therapy. | Lectures | 1.00 | E-Studies platform | |||||
| 8 | Pharmacology of drugs affecting the adrenal cortex. Steroidal and non-steroidal anti-inflammatory drugs. Disease-modifying anti-rheumatic drugs (DMARD). Anti-gout agents. Spinal spondylosis, disc herniation with root irritation syndrome and pain syndrome, pharmacotherapy. Radiculopathies, their treatment. | Lectures | 1.00 | E-Studies platform | |||||
| 9 | Gastroenterology. GERD. Ulcer disease. Nephrology. CKD. Urinary tract infection. | Classes | 1.00 | E-Studies platform | |||||
| 10 | Endocrinology. Osteoporosis. Diabetes mellitus. Hypothyreosis. | Classes | 1.00 | E-Studies platform | |||||
| 11 | Psychiatry/Neurology. Anxiety. Depression. Epilepsy. | Classes | 1.00 | E-Studies platform | |||||
| 12 | Neurology/Rheumatology. Chronic pain. Adaptive, non-adaptive pain. Rheumatoid arthritis. | Classes | 1.00 | E-Studies platform | |||||
| Assessment | |||||||||
| Unaided Work: | Reports, systematic reviews of specific medications, their application and use in the treatment process. | ||||||||
| Assessment Criteria: | Simulation of clinical situations during practical classes, modulation of therapy until a positive result is achieved, assessment – passed / failed. Participation in classes is mandatory, missed classes must be re-worked. Intermediate tests. The average grade of the intermediate tests against the grade received in the exam is 50/50. | ||||||||
| Final Examination (Full-Time): | Exam | ||||||||
| Final Examination (Part-Time): | |||||||||
| Learning Outcomes | |||||||||
| Knowledge: | Describe and explain the principles and pharmacokinetic properties of drug groups and active substances, indications, major adverse reactions, contraindications. Characterize and explain the major interaction risks and effects of drug groups on efficacy, toxicity (if applicable). | ||||||||
| Skills: | On completion of the study course, students will be able to describe preparations of pharmacotherapeutic groups, formulate their mechanisms of action, indications and contraindications, as well as side effects, justify and base their opinion on the chosen treatment, modulate the applied therapy in different clinical situations. To argue reasonably on the usefulness of a pharmacotherapeutic strategy in cases of particular disease pathology; to critically analyze the usefulness of pharmacotherapeutic strategies in the context of organ system diseases. | ||||||||
| Competencies: | On completion of the study course, students will be able to: 1. Use theoretical and practical knowledge and competence in clinical pharmacology and the use of medicinal products. 2. Choose the most appropriate medication according to the individual situation in an individualized dosage regimen to ensure optimal patient treatment and disease prevention. 3. Assess the risks and benefits of treatment. 4. Independently obtain, select and analyze information regarding medications, their use and use in the treatment process. 5. Demonstrate a scientific approach to solving topical issues, as well as have good knowledge of specific literature. | ||||||||
| Bibliography | |||||||||
| No. | Reference | ||||||||
| Required Reading | |||||||||
| 1 | Poisoning & Drug Overdose, 8th ed., 2022 | ||||||||
| 2 | Goodman & Gilman's: The Pharmacological Basis of Therapeutics, 14th ed., 2022 | ||||||||
| 3 | RSU E-studiju vide/RSU E-study environment | ||||||||
| 4 | Basic & Clinical Pharmacology, 15th ed., 2020 | ||||||||
| 5 | Medical Pharmacology and Therapeutics, 6th ed., 2022 | ||||||||
| Additional Reading | |||||||||
| 1 | Harrison's Principles of Internal Medicine, 20th ed., 2018 | ||||||||
| 2 | Basic Concepts in Pharmacology: What You Need to Know for Each Drug Class. 6th ed., 2021 | ||||||||
| 3 | Dynamed | ||||||||
| Other Information Sources | |||||||||
| 1 | https://www.drugbank.ca/ | ||||||||
| 2 | https://pubchem.ncbi.nlm.nih.gov/ | ||||||||
| 3 | https://accessmedicine-mhmedical-com.db.rsu.lv/updatesConte… | ||||||||
| 4 | ClinicalKey | ||||||||
