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Histology
Study Course Description
Course Description Statuss:Approved
Course Description Version:1.00
Study Course Accepted:22.02.2024 13:54:58
| Study Course Information | |||||||||
| Course Code: | MK_071 | LQF level: | Level 7 | ||||||
| Credit Points: | 6.67 | ECTS: | 10.00 | ||||||
| Branch of Science: | Clinical Medicine; Histology and Cytology | Target Audience: | Medicine | ||||||
| Study Course Supervisor | |||||||||
| Course Supervisor: | Māra Pilmane | ||||||||
| Study Course Implementer | |||||||||
| Structural Unit: | Department of Morphology | ||||||||
| The Head of Structural Unit: | |||||||||
| Contacts: | Riga, 9 Kronvalda boulevard, aaiak rsu[pnkts]lv, +371 67061551 | ||||||||
| Study Course Planning | |||||||||
| Full-Time - Semester No.1 | |||||||||
| Lectures (count) | 8 | Lecture Length (academic hours) | 2 | Total Contact Hours of Lectures | 16 | ||||
| Classes (count) | 16 | Class Length (academic hours) | 2 | Total Contact Hours of Classes | 32 | ||||
| Total Contact Hours | 48 | ||||||||
| Full-Time - Semester No.2 | |||||||||
| Lectures (count) | 6 | Lecture Length (academic hours) | 2 | Total Contact Hours of Lectures | 12 | ||||
| Classes (count) | 17 | Class Length (academic hours) | 3 | Total Contact Hours of Classes | 51 | ||||
| Total Contact Hours | 63 | ||||||||
| Study course description | |||||||||
| Preliminary Knowledge: | Medical cell biology, cytology; advisable to study histology simultaneously with biology, anatomy, physiology and biochemistry. | ||||||||
| Objective: | Students develop understanding of the main principles of general, special and functional human histology, structure of cells, tissue and organs; morphofunctional correlation between different tissue and organ structures, cell differentiation, regeneration, adaptation and ontogenetic changes; students develop skills in widely used light microscopy, immunohistochemical and electron microscopy methods; they develop understanding of the significance of morphology in daily clinical work; the students develop understanding of structure of different organs and systems, particularly morphofunctionality, differences and interactions between the endocrine, neural and immune systems. | ||||||||
| Topic Layout (Full-Time) | |||||||||
| No. | Topic | Type of Implementation | Number | Venue | |||||
| 1 | Epithelia. | Lectures | 1.00 | auditorium | |||||
| 2 | Connective tissue | Lectures | 1.00 | auditorium | |||||
| 3 | Nerve tissue. CNS. | Lectures | 1.00 | auditorium | |||||
| 4 | Supportive tissue and development of bones. | Lectures | 1.00 | auditorium | |||||
| 5 | Muscle tissue. | Lectures | 1.00 | auditorium | |||||
| 6 | Blood. | Lectures | 1.00 | auditorium | |||||
| 7 | Hemopoietic and immune organs. | Lectures | 1.00 | auditorium | |||||
| 8 | Sense organs. | Lectures | 1.00 | auditorium | |||||
| 9 | Cytology I: general organelles of the cell. | Classes | 1.00 | Institute of Anatomy and Anthropology | |||||
| 10 | Cytology II: specialized cell organelles and inclusions. | Classes | 1.00 | Institute of Anatomy and Anthropology | |||||
| 11 | Epithelia. | Classes | 1.00 | Institute of Anatomy and Anthropology | |||||
| 12 | Connective tissue. | Classes | 1.00 | Institute of Anatomy and Anthropology | |||||
| 13 | Nerve tissue and peripheral nervous system. | Classes | 1.00 | Institute of Anatomy and Anthropology | |||||
| 14 | Central nervous system. | Classes | 1.00 | Institute of Anatomy and Anthropology | |||||
| 15 | Colloquium I. Cytology. Epithelia. Connective tissue. Nerve tissue. PNS and CNS. Specimens of the practical works No. 1-6. | Classes | 1.00 | Institute of Anatomy and Anthropology | |||||
| 16 | Supportive tissue: cartilage and bone. | Classes | 1.00 | Institute of Anatomy and Anthropology | |||||
| 17 | Bone development. | Classes | 1.00 | Institute of Anatomy and Anthropology | |||||
| 18 | Muscle tissue. | Classes | 1.00 | Institute of Anatomy and Anthropology | |||||
| 19 | Blood vessels. | Classes | 1.00 | Institute of Anatomy and Anthropology | |||||
| 20 | Blood. Haematopoiesis. | Classes | 1.00 | Institute of Anatomy and Anthropology | |||||
| 21 | Haematopoietic and immune organs. Immune system. | Classes | 1.00 | Institute of Anatomy and Anthropology | |||||
| 22 | Colloquium II. Supportive tissue: cartilage and bone. Bone development. Muscle tissue. Blood vessels. Blood, haematopoietic and immune organs. Specimens of the practical works No. 8-13. | Classes | 1.00 | Institute of Anatomy and Anthropology | |||||
| 23 | Skin and its derivatives. | Classes | 1.00 | Institute of Anatomy and Anthropology | |||||
| 24 | Organ of vision. Eyeball. | Classes | 1.00 | Institute of Anatomy and Anthropology | |||||
| 25 | Respiratory system. | Lectures | 1.00 | auditorium | |||||
| 26 | Oral cavity. Tooth development and structure. | Lectures | 1.00 | auditorium | |||||
| 27 | Digestive system structure: Stomach, small intestine, large intestine. | Lectures | 1.00 | auditorium | |||||
| 28 | Gastrointestinal system digestive glands: Pancreas. Liver. | Lectures | 1.00 | auditorium | |||||
| 29 | Reproductive system. | Lectures | 1.00 | auditorium | |||||
| 30 | Neuroendocrine system. | Lectures | 1.00 | auditorium | |||||
| 31 | Organ of hearing. Anatomy of the ear. | Classes | 1.00 | Institute of Anatomy and Anthropology | |||||
| 32 | Seminar: Skin and its derivatives. Sense organs – recognition of slides/analysis of mistakes (4 academic hours). | Classes | 1.00 | Institute of Anatomy and Anthropology | |||||
| 33 | Respiratory system. | Classes | 1.00 | Institute of Anatomy and Anthropology | |||||
| 34 | Gastrointestinal system I. | Classes | 1.00 | Institute of Anatomy and Anthropology | |||||
| 35 | Gastrointestinal system II. | Classes | 1.00 | Institute of Anatomy and Anthropology | |||||
| 36 | Gastrointestinal system III. | Classes | 1.00 | Institute of Anatomy and Anthropology | |||||
| 37 | Gastrointestinal system IV. | Classes | 1.00 | Institute of Anatomy and Anthropology | |||||
| 38 | Gastrointestinal system V. | Classes | 1.00 | Institute of Anatomy and Anthropology | |||||
| 39 | Colloquium III. Respiratory and gastrointestinal systems. Specimens of the practical works No. 3.-8. | Classes | 1.00 | Institute of Anatomy and Anthropology | |||||
| 40 | Excretory system. | Classes | 1.00 | Institute of Anatomy and Anthropology | |||||
| 41 | Male reproductive system. | Classes | 1.00 | Institute of Anatomy and Anthropology | |||||
| 42 | Female reproductive system I. | Classes | 1.00 | Institute of Anatomy and Anthropology | |||||
| 43 | Female reproductive system II. | Classes | 1.00 | Institute of Anatomy and Anthropology | |||||
| 44 | Neuroendocrine system. | Classes | 1.00 | Institute of Anatomy and Anthropology | |||||
| 45 | Diffuse neuroendocrine system. | Classes | 1.00 | Institute of Anatomy and Anthropology | |||||
| 46 | Colloquium IV. Excretory system. Reproductive system. Neuroendocrine system. Specimens of the practical works No. 10-15. | Classes | 1.00 | Institute of Anatomy and Anthropology | |||||
| 47 | Role of morphological diagnostic methods in the daily clinical doctor’s practice. Demonstration of most common mistakes of morphological diagnostic methods. | Classes | 1.00 | Institute of Anatomy and Anthropology | |||||
| Assessment | |||||||||
| Unaided Work: | Students do their independent learning when analysing the structure of histological slides in the laboratory and preparing the protocols of their practical work. Individual work with the recommended literature, according to the topic of lectures and practical classes. Preparation of small group presentations according to the topics of the course. Analysis of the results of scientific publications to raise awareness of the study course. In order to evaluate the quality of the study course as a whole, the student must fill out the study course evaluation questionnaire on the Student Portal. | ||||||||
| Assessment Criteria: | Regular attendance of practical classes. Laboratory class protocols of appropriate quality and submitted in due time. Colloquia include assessment of theoretical knowledge and practical skills acquired. End-of-course oral examination testing students’ theoretical knowledge (50%) of tissue and organ morphology and practical skills (50%) in analysing specimens and schematic images. Students show how to specify age-related changes in tissues and organs. They demonstrate their understanding of important processes and functions in the tissues and organs and the ability to relate morphology with the processes. | ||||||||
| Final Examination (Full-Time): | Exam (Oral) | ||||||||
| Final Examination (Part-Time): | |||||||||
| Learning Outcomes | |||||||||
| Knowledge: | On completion of the study course students will know and will be able to explain differences between general, special and functional histology. They will be able to interpret characteristic structural features of each tissue group and main organs; to describe differences between structures during ageing and adaptation processes. Students will be able to systematise morphological research methods and their use in daily work of a doctor. | ||||||||
| Skills: | On completion of the study course, students will be able to distinguish between the main tissue groups and the structure of the main organs in microscope and schemes; they will be able to describe and evaluate quality, information, interactions and localization of the visible tissue structures in histological slides; they will be able to record histological specimens and to obtain, assess, classify and compare information from the latest special literature and present histological schemes in the subject. | ||||||||
| Competencies: | Upon combining theoretical knowledge and practical skills, the students will be able to implement them in an unified integrative diagnostic activity. Students will be able to recognize tissue and organ morphology and structure in clinical specimens and pictures of the science of morphology. They will be able to distinguish between healthy and pathological tissues. The students will be able to assess the quality of the specimen and the way they can be used for clinic. | ||||||||
| Bibliography | |||||||||
| No. | Reference | ||||||||
| Required Reading | |||||||||
| 1 | Dālmane, A. 2010. Histoloģija. LU Akad. apg. ISBN10: 9984770427, ISBN13: 9789984770420. Latviešu valodā jaunāks, precīzāks, atkārtots izdevums nav pieejams. Esošais izdevums ir akceptējams tā precizitātes dēļ un to ir sarakstījuši katedras docētāji. | ||||||||
| 2 | Groma V., Zalcmane V. 2012. Šūna: uzbūve, funkcijas, molekulārie pamati. RSU publ., 284 lpp. Latviešu valodā jaunāks, precīzāks, atkārtots izdevums nav pieejams. Esošais izdevums ir akceptējams tā precizitātes dēļ un to ir sarakstījuši katedras docētāji. | ||||||||
| 3 | Ross Michael H., Pawlina W. 2018. Histology: A Text and Atlas: With Correlated Cell and Molecular Biology. 8th Edition. LWW. 928 p. ISBN-10 :1496383427 | ||||||||
| 4 | Eroschenko Victor P. 2013. Atlas of Histology with Functional Correlations. 13th Edition. LWW. 617 p. ISBN-10: 1496316762 | ||||||||
| 5 | Kierszenbaum Abraham L., Tres Laura. 2019. Histology and Cell Biology: An Introduction to Pathology. 5th Edition. Elsevier. 824 p. ISBN: 9780323673211 | ||||||||
| 6 | Lowe J., Anderson P., Anderson S. 2018. Stevens & Lowe's Human Histology. 5th Edition. Elsevier. 440 p. ISBN: 9780323612807 | ||||||||
| 7 | Mescher Anthony L. 2021. Junqueira's Basic Histology: Text and Atlas. 16th Edition. McGraw-Hill Education. 480 p. ISBN-10:1260462986 | ||||||||
| 8 | Ovalle William K., Nahirney Patrick C. 2020. Netter's Essential Histology. 3rd Edition. 568 p. ISBN-10:0323694640 | ||||||||
| 9 | Suvarna Kim S., Layton Christopher, Bancroft John D. 2019. Bancroft's Theory and Practice of Histological Techniques. 8th Edition. Elsevier. 584 p. | ||||||||
| 10 | Gartner Leslie P. 2020. Textbook of Histology. 5th Edition. Elsevier. 704 p. ISBN: 9780323672726 | ||||||||
| 11 | Ārvalstu studentiem/For international students: | ||||||||
| 12 | Eroschenko Victor P. 2013. Atlas of Histology with Functional Correlations. 13th Edition. LWW. 617 p. ISBN-10: 1496316762 | ||||||||
| 13 | Kierszenbaum Abraham L., Tres Laura. 2019. Histology and Cell Biology: An Introduction to Pathology. 5th Edition. Elsevier. 824 p. ISBN: 9780323673211 | ||||||||
| 14 | Lowe J., Anderson P., Anderson S. 2018. Stevens & Lowe's Human Histology. 5th Edition. Elsevier. 440 p. ISBN: 9780323612807 | ||||||||
| 15 | Ovalle William K., Nahirney Patrick C. 2020. Netter's Essential Histology. 3rd Edition. 568 p. ISBN-10:0323694640 | ||||||||
| Additional Reading | |||||||||
| 1 | Dongmei Cui; John P. Naftel; Jonathan D. Fratkin; William Daley; James C. Lynch; Duane E. Haines; Gongchao Yang. 2011. Atlas of Histology with Functional and Clinical Correlations. LWW. 434 p. ISBN-10: 0781797594, ISBN-13: 978-0781797597. Precīzs un unikāls histoloģisko struktūru attainojums, nav atkārtota izdevuma. | ||||||||
| 2 | Eroschenko Victor P. 2013. diFiore's Atlas of Histology: with Functional Correlations (Atlas of Histology (Di Fiore's)). 13th Edition. LWW. 617 p. ISBN-13: 978-1496316769, ISBN-10: 1496316762 | ||||||||
| 3 | Gartner Leslie P. 2015. BRS Cell Biology and Histology. 8th Edition. Wolters Kluwer Health. 448 p. ISBN-13: 978-1496396358, ISBN-10: 1496396359 | ||||||||
| 4 | Gartner Leslie P., Lee Lisa M. J. 2022. Gartner & Hiatt's Atlas and Text of Histology. 8th Edition. LWW. 648 p. ISBN-13: 978-1975164256, ISBN-10: 1975164253 | ||||||||
| 5 | Hossler Fred. 2014. Ultrastructure Atlas of Human Tissues. 1st Edition. Wiley-Blackwell. 968 p. ISBN-10: 1118284534, ISBN-13: 978-1118284537 | ||||||||
| 6 | Ovalle William K., Nahirney Patrick C. 2020. Netter’s Histology Cut-Out Flash Cards: A companion to Netter's Essential Histology. 2nd Edition. Elsevier. 136 p. ISBN-13: 978-0323709675, ISBN-10: 0323709672 | ||||||||
| 7 | Nanci A. 2013. Ten Cate's Oral Histology: Development, Structure, and Function. 9th Edition. Elsevier. 352 p. ISBN-13: 978-0323485241, ISBN-10: 0323485243 | ||||||||
| 8 | Young Barbara, O'Dowd Geraldine, Woodford Phillip. 2013. Wheater's Functional Histology: A Text and Colour Atlas. 6th Edition. Churchill Livingstone. 464 p. ISBN-10: 0702047473, ISBN-13: 978-0702047473 | ||||||||
| 9 | Zhang Guiyun, Fenderson Bruce A. 2014. Lippincott's Illustrated Q&A Review of Histology. LWW. 360 p. ISBN-10: 1451188307, ISBN-13: 978-1451188301 | ||||||||
| 10 | Gartner Leslie P. Color Atlas and Text of Histology. 2014. 7th edition. LWW. ISBN13: 9781496346735, ISBN10: 1496346734 | ||||||||
| Other Information Sources | |||||||||
| 1 | http://www.med.uiuc.edu/histo/large/atlas/ | ||||||||
| 2 | http://www.kumc.edu/instruction/medicine/anatomy/histoweb/ | ||||||||
| 3 | http://www.visualhistology.com/Visual_Histology_Atlas/ | ||||||||
| 4 | http://www.meddean.luc.edu/LUMEN/MedEd/Histo/frames/histo_f… | ||||||||
| 5 | http://141.214.65.171/Histology/view.apml | ||||||||
| 6 | http://histologyguide.com/slidebox/slidebox.html | ||||||||
