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Pharmaceutical Dosage Form Technology
Study Course Description
Course Description Statuss:Approved
Course Description Version:2.00
Study Course Accepted:01.07.2024 09:58:06
| Study Course Information | |||||||||
| Course Code: | ZFTK_063 | LQF level: | Level 7 | ||||||
| Credit Points: | 7.33 | ECTS: | 11.00 | ||||||
| Branch of Science: | Basic Sciences of Medicine, including Pharmacy; Technology of Drug Forms | Target Audience: | Pharmacy | ||||||
| Study Course Supervisor | |||||||||
| Course Supervisor: | Olga Kiseļova | ||||||||
| Study Course Implementer | |||||||||
| Structural Unit: | Department of Applied Pharmacy | ||||||||
| The Head of Structural Unit: | |||||||||
| Contacts: | Riga, 16 Konsula Street, zftk rsu[pnkts]lv, +371 67061547 | ||||||||
| Study Course Planning | |||||||||
| Full-Time - Semester No.1 | |||||||||
| Lectures (count) | 9 | Lecture Length (academic hours) | 2 | Total Contact Hours of Lectures | 18 | ||||
| Classes (count) | 8 | Class Length (academic hours) | 4 | Total Contact Hours of Classes | 32 | ||||
| Total Contact Hours | 50 | ||||||||
| Full-Time - Semester No.2 | |||||||||
| Lectures (count) | 9 | Lecture Length (academic hours) | 2 | Total Contact Hours of Lectures | 18 | ||||
| Classes (count) | 11 | Class Length (academic hours) | 4 | Total Contact Hours of Classes | 44 | ||||
| Total Contact Hours | 62 | ||||||||
| Study course description | |||||||||
| Preliminary Knowledge: | Inorganic chemistry, organic chemistry, physical pharmacy, mathematics, plant and animal biology, pharmacognosy, microbiology, pharmaceutical chemistry. | ||||||||
| Objective: | The objective of the study course is to provide an opportunity to learn the theoretical foundations of pharmaceutical dosage form preparation and the practical skills required for the preparation of different dosage forms in a pharmacy. | ||||||||
| Topic Layout (Full-Time) | |||||||||
| No. | Topic | Type of Implementation | Number | Venue | |||||
| 1 | Powders as a dosage form, characteristics and preparation thereof. | Lectures | 3.00 | E-Studies platform | |||||
| 2 | Preparation of simple and compound powder formulae. | Classes | 4.00 | laboratory | |||||
| 3 | Liquid dosage forms, characteristics and preparation thereof. | Lectures | 4.00 | E-Studies platform | |||||
| 4 | Preparation of aqueous and non-aqueous solutions for different formulae. | Classes | 3.00 | laboratory | |||||
| 5 | Characteristics and preparation of mixtures as a dosage form. | Lectures | 2.00 | E-Studies platform | |||||
| 6 | Characteristics and preparation of mixtures as a dosage form (continuation of the topic). | Lectures | 1.00 | E-Studies platform | |||||
| 7 | Preparation of different mixture formulae. | Classes | 1.00 | laboratory | |||||
| 8 | Preparation of different mixture formulae. | Classes | 2.00 | laboratory | |||||
| 9 | Characterisation and preparation of drops as a dosage form. | Lectures | 1.00 | E-Studies platform | |||||
| 10 | Preparation of different drops formulae. | Classes | 1.00 | laboratory | |||||
| 11 | Characteristics and preparation of suspensions as a dosage form. | Lectures | 3.00 | E-Studies platform | |||||
| 12 | Preparation of different suspension formulae. | Classes | 3.00 | laboratory | |||||
| 13 | Ointments as a dosage form, characteristics and preparation thereof. | Lectures | 3.00 | E-Studies platform | |||||
| 14 | Preparation of different ointment formulae. | Classes | 4.00 | laboratory | |||||
| 15 | Suppositories as a dosage form, characteristics and preparation thereof. | Lectures | 1.00 | E-Studies platform | |||||
| 16 | Preparation of different suppository formulae. | Classes | 1.00 | laboratory | |||||
| Assessment | |||||||||
| Unaided Work: | Individual work – to write a report on the prescriptions prepared in each practical class and solve situational problems. In order to evaluate the quality of the study course as a whole, the student must fill out the study course evaluation questionnaire on the Student Portal. | ||||||||
| Assessment Criteria: | Successfully passed 4 theoretical test works for full-time students. The first semester test consists of a set of solved situational problems. An exam consisting of 1 written theoretical questions and two prescription formulas. | ||||||||
| Final Examination (Full-Time): | Exam (Written) | ||||||||
| Final Examination (Part-Time): | |||||||||
| Learning Outcomes | |||||||||
| Knowledge: | As a result of successfully completing the study course, the student: 1. Will have the knowledge of the theoretical basis of the preparation of pharmaceutical dosage forms. 2. Will be able to answer questions about the preparation of dosage forms in a pharmacy. 3. Will be able to explain and justify the order of addition of ingredients to each dosage form. | ||||||||
| Skills: | As a result of completing the study course, the student will be able: 1. To apply the methods of dosage form technology to the preparation of medicinal products in a pharmacy setting; 2. To prepare a variety of dosage forms with sufficient speed and quality; 3. To assess the quality of prepared dosage forms and explain their use. | ||||||||
| Competencies: | As a result of completing the study course, students will be able to prepare medicinal products according to individual formulae in the pharmacy. | ||||||||
| Clinical Skills: | |||||||||
| No. | Skill | Level | |||||||
| 1 | Compounding of suspensions for external use | B1 - Basic level | |||||||
| Bibliography | |||||||||
| No. | Reference | ||||||||
| Required Reading | |||||||||
| 1 | Bouwman-Boer, Y., Fenton-May, V. and Le Brun, P., eds. 2015. Practical Pharmaceutics: An International Guideline for the Preparations, Care and Use of Medicinal Products. 1st ed. Heidelberg: Springer International Publishing. | ||||||||
| 2 | Marriott, J. F., Wilson, K. A., Langley C. A. and Belcher, D. 2010. Pharmaceutical Compounding and Dispensing. 2nd ed. London: Pharmaceutical Press. | ||||||||
| 3 | Kiseļova, O. 2022. Ekstemporālo zāļu pieejamība Latvijas aptiekās: situācijas kvantitatīvs un kvalitatīvs novērtējums un nākotnes perspektīva. Rīga: RSU. | ||||||||
| 4 | Ministru Kabinets. 23.03.2005. Recepšu veidlapu izgatavošanas un uzglabāšanas, kā arī recepšu izrakstīšanas un uzglabāšanas noteikumi. MK noteikumi Nr. 175. Latvijas Vēstnesis. 48. | ||||||||
| 5 | Ministru Kabinets. 08.05.2006. Noteikumi par zāļu ražošanas un kontroles kārtību, par zāļu ražošanu atbildīgās amatpersonas kvalifikācijas prasībām un profesionālo pieredzi un kārtību, kādā zāļu ražošanas uzņēmumam izsniedz labas ražošanas prakses sertifikātu. MK noteikumi Nr. 304. Latvijas Vēstnesis. 70. | ||||||||
| Additional Reading | |||||||||
| 1 | Kiselova, O., Maurina, B., Sidlovska, V. 2020. Analysis of extemporaneous prescriptions prescribed by dermatovenerologists in Latvia and comparison with standardized compounded preparation monographs of Germany and USA. Medicina. 56(1), 29. | ||||||||
| 2 | Kiselova, O., Maurina, B., Sidlovska, V., Zvejnieks, J. 2019. The extent of extemporaneous preparation and regulatory framework of extemporaneous compounding in Latvia. Medicina. 55(9), 531. | ||||||||
| 3 | Handbook of extemporaneous preparation: a guide to pharmaceutical compounding / edited by Mark Jackson, Andrew Lowey, on behalf of the NHS Pharmaceutical Quality Assurance Committee. London: Pharmaceutical Press. 2010, xvi, 464 p. | ||||||||
| 4 | Voigt, Rudolf. Voigt Pharmazeutische Technologie. Berlin/Wiesbaden, 2021. - 800 p. | ||||||||
| 5 | Bauer, Frömming, Führer. Pharmazeutische Technologie mit Einführung in Biopharmazie und Biotechnologie. 2022 | ||||||||
| 6 | Sandell, Erik. Pharmaceutics. Swedish Pharmaceutical Press. Stockholm, 1983. - 242 p. | ||||||||
