Basics of Neuroscience

Study Course Description

Course Description Statuss:Approved

Course Description Version:6.00

Study Course Accepted:07.11.2022 13:51:41

Study Course Information
Course Code:		MK_031		LQF level:		Level 7
Credit Points:		2.00		ECTS:		3.00
Branch of Science:		Clinical Medicine; Histology and Cytology		Target Audience:		Life Science
Study Course Supervisor
Course Supervisor:		Māra Pilmane
Study Course Implementer
Structural Unit:		Department of Morphology
The Head of Structural Unit:
Contacts:		Riga, 9 Kronvalda boulevard, aaiakrsu[pnkts]lv, +371 67061551
Study Course Planning
Full-Time - Semester No.1
Lectures (count)		8	Lecture Length (academic hours)		2	Total Contact Hours of Lectures		16
Classes (count)		4	Class Length (academic hours)		2	Total Contact Hours of Classes		8
Total Contact Hours								24
Study course description
Preliminary Knowledge:
Biology, medical cell biology, histology and embryology, physiology, biochemistry, also recommended: anatomy.
Objective:
The aim of the study course is to develop students’ understanding of the development of the components of the human peripheral and central nervous system, the morpho-functional components, in particular the plasticity of the neuron structure, the structure and function of central and peripheral coordination of senses such as touch, vision, movement, thought, pain, hearing, smell, taste analysers, age-related changes, compensatory and adaptive responses and morpho-functional regularities in the case of normal state and under the oxidative stress conditions. At the same time the aim is to familiarise students with modern evaluation methods of morphological and functional regularities of these central and peripheral structures.
Topic Layout (Full-Time)
No.	Topic			Type of Implementation		Number	Venue
1	Neuron biology. Morphofunctional NS anatomy.			Lectures		1.00	Institute of Anatomy and Anthropology
2	Tactile sense: peripheral and central mechanisms.			Lectures		1.00	Institute of Anatomy and Anthropology
3	Movement: muscle, motoneuronal unit, spinal integration, brain stem, brain and cerebellar cortex and central control.			Lectures		1.00	Institute of Anatomy and Anthropology
4	Smell and taste: morphofunctional provision and its central regulation.			Lectures		1.00	Institute of Anatomy and Anthropology
5	Vision: morphofunctional provision and its central regulation.			Lectures		1.00	Institute of Anatomy and Anthropology
6	Hearing: morphofunctional provision and its central regulation.			Lectures		1.00	Institute of Anatomy and Anthropology
7	Thoughts’ and affective disorders: morphofunctional provision and its central regulation.			Lectures		1.00	Institute of Anatomy and Anthropology
8	Development of the peripheral nervous system (PNS) and the central nervous system (CNS).			Lectures		1.00	Institute of Anatomy and Anthropology
9	The smallest basic units of the NS.			Classes		1.00	Institute of Anatomy and Anthropology
10	Sensory epithelium and its interactions with other PNS and CNS structures/centres.			Classes		1.00	Institute of Anatomy and Anthropology
11	Hystophysiology of CNS: Brodman map and the main centres.			Classes		1.00	Institute of Anatomy and Anthropology
12	Final test.			Classes		1.00	Institute of Anatomy and Anthropology
Assessment
Unaided Work:
Within the study course, individual work is organised by analysing micropreparations. Individual work with the recommended literature, according to the topics of lectures and classes. Preparation of presentations in small groups, according to the topics of the course. Analysis of the results of scientific publications to deepen the understanding of the subject.
Assessment Criteria:
An oral examination (100% of the grade) is planned at the end of the study course, during which the students' theoretical knowledge of the morphology of nervous tissue and sensory organs is tested in the form of essay questions. Part of the examination assessment is a grade for independent work in preparing a presentation. The examination tests knowledge of the morphology of tissues and organs and their age-related changes and plasticity. Students are given the opportunity to demonstrate an understanding of the important processes and functions of tissues and organs, and the ability to relate morphology to biological processes.
Final Examination (Full-Time):		Exam (Oral)
Final Examination (Part-Time):
Learning Outcomes
Knowledge:		Understand the components of the human PNS and CNS, the major developmental stages of the nervous system, the central and peripheral mechanisms of touch, movement, vision, hearing, smell, taste, thought, and the major regulators, and the age-related changes and plasticity of these sensory structures as functions change. Know and be able to apply morphological research methods used in neuroscience.
Skills:		Identify neurological slides among other morphological slides; distinguish between different sensory structures visually and decide the need for additional morphological information in case of a poor-quality slide/schema.
Competencies:		Discuss the preparation and evaluation of specific neuromorphology slides/schemas, be familiar with the main neuroscience subject areas and directions.
Bibliography
No.	Reference
Required Reading
1	Siegel, A., Hreday N. S. 2018. Essential neuroscience. 4th Edition. LWW. 648 p. ISBN-13: 978-1496382405, ISBN-10: 1496382404
2	Purves D., Augustine G.J., Fitzpatrick D., et.al. 2017. Neuroscience. 6th Edition. Oxford University Press. 960 p. ISBN-13: 978-1605353807, ISBN-10: 1605353809
3	Barker R.A., Cicchetti F., Robinson E.S.J. 2017. Neuroanatomy and Neuroscience at a Glance, 4th Edition, Wiley-Blackwell, p. 158. ISBN 978-1-119-16841-6
4	Splittgerber R. 2019. Snell`s Clinical Neuroanatomy, 8th Edition, Wolters Kluwer, p. 527. ISBN-13:978-1-4963-4675-9, ISBN-10:4963-4675-0
5	Felten D.L., O`Banion M.K., Maida M. 2021. Netter`s atlas of Neuroscience, 4th Edition, Elsevier, p. 477. ISBN 9780323756556
6	Haines D.E. 2018. Neuroanatomy Atlas in Clinical Context: Structures, Sections, Systems, and Syndromes. 10th Edition, Wolters Kluwer, p. 369 ISBN-13: 978-1496384164, ISBN-10: 975106-68-7
7	Bear M.F., Connors B.W., Paradiso M.A. 2015. Neuroscience: Exploring the Brain, 4th Edition, Wolters Kluwer, p. 975. ISBN – 13: 978-1-4511-0954-2; ISBN-10:1-4511-0954-7
8	Vanderah T., Gould D.J. 2021. Nolte's The Human Brain: An Introduction to its Functional Anatomy. 8th Edition. Elsevier. 720 p. ISBN-13: 978-1455728596, ISBN-10: 1455728594
9	Martin J. 2020. Neuroanatomy Text and Atlas. 5th Edition. McGraw Hill. 544 p. ISBN-13: 978-1259642487, ISBN-10: 1259642488
10	Mtui E., Gruener G., Dockery P. 2021. Fitzgerald`s clinical Neuroanatomy and Neuroscience, 8th Edition, Elsevier, p. 414. ISBN 978-0-7020-7909-2.
Additional Reading
1	Mescher Anthony L. 2021. Junqueira's Basic Histology: Text and Atlas. 16th Edition. McGraw-Hill Education. 480 p. ISBN-10:1260462986, ISBN-13:978-1260462982
2	Ovalle William K.,‎ Nahirney Patrick C. 2020. Netter's Essential Histology. 3rd Edition. Elsevier. 568 p. ISBN-10:0323694640, ISBN-13:978-0323694643
3	Gartner Leslie P. 2018. BRS Cell Biology and Histology. 8th Edition. Wolters Kluwer Health. 448 p. ISBN-13: 978-1496396358, ISBN-10: 1496396359
4	Vanderah T.W. 2018. Nolte`s Essentials of the Human Brain, 2nd Edition, Elsevier, p. 208. ISBN 978-0-323-52931-0
5	Kierszenbaum Abraham L.,‎ Tres Laura. 2019. Histology and Cell Biology: An Introduction to Pathology. 5th Edition. Elsevier. 824 p. ISBN: 9780323673211, ISBN: 9780323683784
6	Gartner Leslie P. 2020. Textbook of Histology. 5th Edition. Elsevier. 704 p. ISBN: 9780323672726, ISBN: 9780323672740
7	O`Dowd G., Bell S., Wright S. 2023. Wheater`s Functional Histology. 7th Edition, Elsevier, p. 464. ISBN-10:0702083348, ISBN-13: 978-0702083341
Other Information Sources
1	http://www.med.uiuc.edu/histo/large/atlas/
2	http://www.kumc.edu/instruction/medicine/anatomy/histoweb/
3	http://www.visualhistology.com/Visual_Histology_Atlas/
4	http://www.meddean.luc.edu/LUMEN/MedEd/Histo/frames/histo_f…
5	http://histologyguide.com/slidebox/slidebox.html