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Histology

Study Course Description

Course Description Statuss:Approved
Course Description Version:1.00
Study Course Accepted:22.02.2024 13:54:58
Study Course Information
Course Code:MK_071LQF level:Level 7
Credit Points:6.67ECTS:10.00
Branch of Science:Clinical Medicine; Histology and CytologyTarget Audience:Medicine
Study Course Supervisor
Course Supervisor:Māra Pilmane
Study Course Implementer
Structural Unit:Department of Morphology
The Head of Structural Unit:
Contacts:Riga, 9 Kronvalda boulevard, aaiakatrsu[pnkts]lv, +371 67061551
Study Course Planning
Full-Time - Semester No.1
Lectures (count)8Lecture Length (academic hours)2Total Contact Hours of Lectures16
Classes (count)16Class Length (academic hours)2Total Contact Hours of Classes32
Total Contact Hours48
Full-Time - Semester No.2
Lectures (count)6Lecture Length (academic hours)2Total Contact Hours of Lectures12
Classes (count)17Class Length (academic hours)3Total Contact Hours of Classes51
Total Contact Hours63
Study course description
Preliminary Knowledge:
Medical cell biology, cytology; advisable to study histology simultaneously with biology, anatomy, physiology and biochemistry.
Objective:
Students develop understanding of the main principles of general, special and functional human histology, structure of cells, tissue and organs; morphofunctional correlation between different tissue and organ structures, cell differentiation, regeneration, adaptation and ontogenetic changes; students develop skills in widely used light microscopy, immunohistochemical and electron microscopy methods; they develop understanding of the significance of morphology in daily clinical work; the students develop understanding of structure of different organs and systems, particularly morphofunctionality, differences and interactions between the endocrine, neural and immune systems.
Topic Layout (Full-Time)
No.TopicType of ImplementationNumberVenue
1Epithelia.Lectures1.00auditorium
2Connective tissueLectures1.00auditorium
3Nerve tissue. CNS.Lectures1.00auditorium
4Supportive tissue and development of bones.Lectures1.00auditorium
5Muscle tissue.Lectures1.00auditorium
6Blood.Lectures1.00auditorium
7Hemopoietic and immune organs.Lectures1.00auditorium
8Sense organs.Lectures1.00auditorium
9Cytology I: general organelles of the cell.Classes1.00Institute of Anatomy and Anthropology
10Cytology II: specialized cell organelles and inclusions.Classes1.00Institute of Anatomy and Anthropology
11Epithelia.Classes1.00Institute of Anatomy and Anthropology
12Connective tissue.Classes1.00Institute of Anatomy and Anthropology
13Nerve tissue and peripheral nervous system.Classes1.00Institute of Anatomy and Anthropology
14Central nervous system.Classes1.00Institute of Anatomy and Anthropology
15Colloquium I. Cytology. Epithelia. Connective tissue. Nerve tissue. PNS and CNS. Specimens of the practical works No. 1-6.Classes1.00Institute of Anatomy and Anthropology
16Supportive tissue: cartilage and bone.Classes1.00Institute of Anatomy and Anthropology
17Bone development.Classes1.00Institute of Anatomy and Anthropology
18Muscle tissue.Classes1.00Institute of Anatomy and Anthropology
19Blood vessels.Classes1.00Institute of Anatomy and Anthropology
20Blood. Haematopoiesis.Classes1.00Institute of Anatomy and Anthropology
21Haematopoietic and immune organs. Immune system.Classes1.00Institute of Anatomy and Anthropology
22Colloquium II. Supportive tissue: cartilage and bone. Bone development. Muscle tissue. Blood vessels. Blood, haematopoietic and immune organs. Specimens of the practical works No. 8-13.Classes1.00Institute of Anatomy and Anthropology
23Skin and its derivatives.Classes1.00Institute of Anatomy and Anthropology
24Organ of vision. Eyeball.Classes1.00Institute of Anatomy and Anthropology
25Respiratory system.Lectures1.00auditorium
26Oral cavity. Tooth development and structure.Lectures1.00auditorium
27Digestive system structure: Stomach, small intestine, large intestine.Lectures1.00auditorium
28Gastrointestinal system digestive glands: Pancreas. Liver.Lectures1.00auditorium
29Reproductive system.Lectures1.00auditorium
30Neuroendocrine system.Lectures1.00auditorium
31Organ of hearing. Anatomy of the ear.Classes1.00Institute of Anatomy and Anthropology
32Seminar: Skin and its derivatives. Sense organs – recognition of slides/analysis of mistakes (4 academic hours).Classes1.00Institute of Anatomy and Anthropology
33Respiratory system.Classes1.00Institute of Anatomy and Anthropology
34Gastrointestinal system I.Classes1.00Institute of Anatomy and Anthropology
35Gastrointestinal system II.Classes1.00Institute of Anatomy and Anthropology
36Gastrointestinal system III.Classes1.00Institute of Anatomy and Anthropology
37Gastrointestinal system IV.Classes1.00Institute of Anatomy and Anthropology
38Gastrointestinal system V.Classes1.00Institute of Anatomy and Anthropology
39Colloquium III. Respiratory and gastrointestinal systems. Specimens of the practical works No. 3.-8.Classes1.00Institute of Anatomy and Anthropology
40Excretory system.Classes1.00Institute of Anatomy and Anthropology
41Male reproductive system.Classes1.00Institute of Anatomy and Anthropology
42Female reproductive system I.Classes1.00Institute of Anatomy and Anthropology
43Female reproductive system II.Classes1.00Institute of Anatomy and Anthropology
44Neuroendocrine system.Classes1.00Institute of Anatomy and Anthropology
45Diffuse neuroendocrine system.Classes1.00Institute of Anatomy and Anthropology
46Colloquium IV. Excretory system. Reproductive system. Neuroendocrine system. Specimens of the practical works No. 10-15.Classes1.00Institute of Anatomy and Anthropology
47Role of morphological diagnostic methods in the daily clinical doctor’s practice. Demonstration of most common mistakes of morphological diagnostic methods.Classes1.00Institute of Anatomy and Anthropology
Assessment
Unaided Work:
Students do their independent learning when analysing the structure of histological slides in the laboratory and preparing the protocols of their practical work. Individual work with the recommended literature, according to the topic of lectures and practical classes. Preparation of small group presentations according to the topics of the course. Analysis of the results of scientific publications to raise awareness of the study course. In order to evaluate the quality of the study course as a whole, the student must fill out the study course evaluation questionnaire on the Student Portal.
Assessment Criteria:
Regular attendance of practical classes. Laboratory class protocols of appropriate quality and submitted in due time. Colloquia include assessment of theoretical knowledge and practical skills acquired. End-of-course oral examination testing students’ theoretical knowledge (50%) of tissue and organ morphology and practical skills (50%) in analysing specimens and schematic images. Students show how to specify age-related changes in tissues and organs. They demonstrate their understanding of important processes and functions in the tissues and organs and the ability to relate morphology with the processes.
Final Examination (Full-Time):Exam (Oral)
Final Examination (Part-Time):
Learning Outcomes
Knowledge:On completion of the study course students will know and will be able to explain differences between general, special and functional histology. They will be able to interpret characteristic structural features of each tissue group and main organs; to describe differences between structures during ageing and adaptation processes. Students will be able to systematise morphological research methods and their use in daily work of a doctor.
Skills:On completion of the study course, students will be able to distinguish between the main tissue groups and the structure of the main organs in microscope and schemes; they will be able to describe and evaluate quality, information, interactions and localization of the visible tissue structures in histological slides; they will be able to record histological specimens and to obtain, assess, classify and compare information from the latest special literature and present histological schemes in the subject.
Competencies:Upon combining theoretical knowledge and practical skills, the students will be able to implement them in an unified integrative diagnostic activity. Students will be able to recognize tissue and organ morphology and structure in clinical specimens and pictures of the science of morphology. They will be able to distinguish between healthy and pathological tissues. The students will be able to assess the quality of the specimen and the way they can be used for clinic.
Bibliography
No.Reference
Required Reading
1Dālmane, A. 2010. Histoloģija. LU Akad. apg. ISBN10: 9984770427, ISBN13: 9789984770420. Latviešu valodā jaunāks, precīzāks, atkārtots izdevums nav pieejams. Esošais izdevums ir akceptējams tā precizitātes dēļ un to ir sarakstījuši katedras docētāji.
2Groma V., Zalcmane V. 2012. Šūna: uzbūve, funkcijas, molekulārie pamati. RSU publ., 284 lpp. Latviešu valodā jaunāks, precīzāks, atkārtots izdevums nav pieejams. Esošais izdevums ir akceptējams tā precizitātes dēļ un to ir sarakstījuši katedras docētāji.
3Ross Michael H.,‎ Pawlina W. 2018. Histology: A Text and Atlas: With Correlated Cell and Molecular Biology. 8th Edition. LWW. 928 p. ISBN-10 :1496383427
4Eroschenko Victor P. 2013. Atlas of Histology with Functional Correlations. 13th Edition. LWW. 617 p. ISBN-10: 1496316762
5Kierszenbaum Abraham L.,‎ Tres Laura. 2019. Histology and Cell Biology: An Introduction to Pathology. 5th Edition. Elsevier. 824 p. ISBN: 9780323673211
6Lowe J., Anderson P., Anderson S. 2018. Stevens & Lowe's Human Histology. 5th Edition. Elsevier. 440 p. ISBN: 9780323612807
7Mescher Anthony L. 2021. Junqueira's Basic Histology: Text and Atlas. 16th Edition. McGraw-Hill Education. 480 p. ISBN-10:1260462986
8Ovalle William K.,‎ Nahirney Patrick C. 2020. Netter's Essential Histology. 3rd Edition. 568 p. ISBN-10:0323694640
9Suvarna Kim S.,‎ Layton Christopher,‎ Bancroft John D. 2019. Bancroft's Theory and Practice of Histological Techniques. 8th Edition. Elsevier. 584 p.
10Gartner Leslie P. 2020. Textbook of Histology. 5th Edition. Elsevier. 704 p. ISBN: 9780323672726
11Ārvalstu studentiem/For international students:
12Eroschenko Victor P. 2013. Atlas of Histology with Functional Correlations. 13th Edition. LWW. 617 p. ISBN-10: 1496316762
13Kierszenbaum Abraham L.,‎ Tres Laura. 2019. Histology and Cell Biology: An Introduction to Pathology. 5th Edition. Elsevier. 824 p. ISBN: 9780323673211
14Lowe J., Anderson P., Anderson S. 2018. Stevens & Lowe's Human Histology. 5th Edition. Elsevier. 440 p. ISBN: 9780323612807
15Ovalle William K.,‎ Nahirney Patrick C. 2020. Netter's Essential Histology. 3rd Edition. 568 p. ISBN-10:0323694640
Additional Reading
1Dongmei Cui; John P. Naftel; Jonathan D. Fratkin; William Daley; James C. Lynch; Duane E. Haines; Gongchao Yang. 2011. Atlas of Histology with Functional and Clinical Correlations. LWW. 434 p. ISBN-10: 0781797594, ISBN-13: 978-0781797597. Precīzs un unikāls histoloģisko struktūru attainojums, nav atkārtota izdevuma.
2Eroschenko Victor P. 2013. diFiore's Atlas of Histology: with Functional Correlations (Atlas of Histology (Di Fiore's)). 13th Edition. LWW. 617 p. ISBN-13: 978-1496316769, ISBN-10: 1496316762
3Gartner Leslie P. 2015. BRS Cell Biology and Histology. 8th Edition. Wolters Kluwer Health. 448 p. ISBN-13: 978-1496396358, ISBN-10: 1496396359
4Gartner Leslie P., Lee Lisa M. J. 2022. Gartner & Hiatt's Atlas and Text of Histology. 8th Edition. LWW. 648 p. ISBN-13: 978-1975164256, ISBN-10: 1975164253
5Hossler Fred. 2014. Ultrastructure Atlas of Human Tissues. 1st Edition. Wiley-Blackwell. 968 p. ISBN-10: 1118284534, ISBN-13: 978-1118284537
6Ovalle William K.,‎ Nahirney Patrick C. 2020. Netter’s Histology Cut-Out Flash Cards: A companion to Netter's Essential Histology. 2nd Edition. Elsevier. 136 p. ISBN-13: 978-0323709675, ISBN-10: 0323709672
7Nanci A. 2013. Ten Cate's Oral Histology: Development, Structure, and Function. 9th Edition. Elsevier. 352 p. ISBN-13: 978-0323485241, ISBN-10: 0323485243
8Young Barbara, O'Dowd Geraldine, Woodford Phillip. 2013. Wheater's Functional Histology: A Text and Colour Atlas. 6th Edition. Churchill Livingstone. 464 p. ISBN-10: 0702047473, ISBN-13: 978-0702047473
9Zhang Guiyun,‎ Fenderson Bruce A. 2014. Lippincott's Illustrated Q&A Review of Histology. LWW. 360 p. ISBN-10: 1451188307, ISBN-13: 978-1451188301
10Gartner Leslie P. Color Atlas and Text of Histology. 2014. 7th edition. LWW. ISBN13: 9781496346735, ISBN10: 1496346734
Other Information Sources
1http://www.med.uiuc.edu/histo/large/atlas/
2http://www.kumc.edu/instruction/medicine/anatomy/histoweb/
3http://www.visualhistology.com/Visual_Histology_Atlas/
4http://www.meddean.luc.edu/LUMEN/MedEd/Histo/frames/histo_f…
5http://141.214.65.171/Histology/view.apml
6http://histologyguide.com/slidebox/slidebox.html