Multifunctional nano-sized calcium phosphate/hyaluronic acid hydrogels for treatment of osteoporotic bone fractures

Project/agreement No.

6.2.-25/2016/0173

Project funding

148 312.67 EUR, including 73344.03 EUR RSU funding and 74968.64 EUR RTU funding

Project manager

prof. Maija Dambrova, Dagnija Loča (RTU)

Project realization

15.02.2016. - 28.02.2019.

Aim

Development of new, innovative three-dimensional calcium phosphate and hyaluronic acid cross-linked hydrogels with inorganic component up to 60 mass %, which would not cause inflammation in the surrounding tissues, promote angiogenesis processes and form new bone tissues when breaking down over time

Description

Rīga Stradiņš University and Riga Technical University carry out a scientific cooperation project during the period from February 2016 to February 2019 aimed at establishing inter-university research teams, conducting interdisciplinary and competitive studies

Activities of the project

Development of calcium phosphate/hyaluronic acid composites (RTU)

Development of calcium phosphate/hyaluronic acid composites high in CaP (RTU)

Characterisation of physical and chemical features of calcium phosphate/hyaluronic acid composites (RTU)

Calcium phosphate/hyaluronic acid composites in vitro testing (RSU)

Calcium phosphate/hyaluronic acid composites in vivo testing (RSU)

Partner RTU

Faculty of Material Science and Applied Chemistry, Institute of General Chemical Engineering (IGCEI) and Rudolfs Cimdins Riga Biomaterials Innovation and Development Centre (RBIDC)

Partner RSU

The Department of Pharmaceutical Chemistry of the Faculty of Pharmacy, in cooperation with the Latvian Institute of Organic Synthesis

Project results

5 scientific publications have been published

International project application EuroNano, M.ERA-NET, and 2 applications H2020 have been submitted