Fundamental and Applied Research Projects

Current projects

2025–2027

Project	Head of project	Budget total (EUR)
Elucidation of the mechanism of amorphization and dissolution of bad glass former as a function of drug-polymer interaction and preparation method	Valentyn Mohylyuk	300 000
Quince biowaste valorization into targeted drug delivery components and innovative health-promoting agents	Līga Pētersone	300 000

2024–2026

Project	Head of project	Budget total (EUR)
Mitigating Energy Poverty through Innovative Solutions	Karina Palkova (RSU), Laila Zemīte (RTU)	300,000
Socially responsible green transition: strengthening governance solutions to empower Homo Climaticus in the healthcare sector (GreenCare)	Dina Bite	300,000
Hierarchial model approach and experimental validation for typical drug discovery system dissolution profile predictions (ModelDrug)	Agnese Brangule	300,000
The Baltic Russophone identity in flux: Political behavior, boundary making, and media practices after Russia’s full-scale invasion of Ukraine	Mārtiņš Kaprāns (LU); RSU project manager - Jānis Juzefovičs	300,000
Smart textile solutions as biofeedback method for injury prevention for Latvian football youth league players	Guna Semjonova	299,997
Hypoxia-induced molecular alterations and druggable targets in triple negative breast cancer cell lines - HipTNBC	Inese Čakstiņa-Dzērve	300,000

2023–2026

Project	Head of project	Budget total (EUR)
Development of an integrative approach to the assessment of cognitive abilities in patients with neurodegenerative diseases of the central nervous system	Ardis Platkājis	300,000

2023–2025

Project	Head of project	Budget total (EUR)
Dissecting non-transformed B cell responses in chronic lymphocytic leukaemia and multiple myeloma	Sandra Lejniece	300,000
Implementation of the Evidence-Based Paediatric Caries Management Strategies in Latvian Clinical Practice - an Evidence Transfer Study	Ilze Maldupa	300,000
Multiparametric optical technique for fluid resuscitation and vasopressor therapy guidance in critically ill COVID01-19 patients	Andris Grabovskis (LU); Oļegs Sabeļņikovs (RSU)	299,775
Targeting autoimmune mechanisms for the prevention of gastric neuroendocrine tumours	Vita Rovīte (the Latvian Biomedical Research and Study Centre); Ilze Konrāde (RSU)	300,000

2022–2024

Project	Head of project	Budget total (EUR)
(Re)moving Ties: Relatedness in Contemporary Mobile Work Regimes	Klāvs Sedlenieks	299,960.00
SARS-CoV-2 and COVID-19 contexts for pathologies of the hepatobiliary system, their histological, biochemical, radiological and clinical characteristics and possibilities of preventing these pathologies	Ludmila Vīksna	299,999.70
Discovering biomarkers of disease progression and variability in Charcot-Marie-Tooth neuropathy	Viktorija Ķēniņa	299,999.70
The role of clonal hematopoiesis of indeterminate potential as a potential driver of cardiovascular diseases and its association with clinical outcome	Kārlis Trušinskis	299,999.70
Role of metabolome, biomarkers and ultrasound parameters in successful labour induction	Natālija Vedmedovska	299,999.70
A Deep Learning Approach for Osteoporosis Identification using Cone-beam Computed Tomography	Kaspars Sudars (Institute of Electronics and Computer Science), Anda Slaidiņa	299,999.70
Human papillomavirus genome associated correlates of disease progression and treatment response for cervical neoplasms and cancer	Maria Issagouliantis	299,999.70

Previous projects

2021–2023

Project	Head of project	Budget total (EUR)
Quadruple Helix Concept (QHC) as base of the next generation PPP model	Dzintra Atstāja	300,000
Tuberculosis treatment: exploring the perspectives for personalised therapy	Dace Bandere	300,000
Elucidating comprehensive etiology of cervical insufficiency to foster timely diagnosis of preterm delivery and prevent adverse outcomes in obstetrics	Dace Rezeberga	300,000
From indifference to making difference in climate policy: improving the interaction between political narrative and societal perceptions in Latvia	Andris Sprūds	299,544
Implementation of balloon pulmonary angioplasty and evaluation of its effectiveness in treatment of chronic thromboembolic pulmonary hypertension at Pauls Stradins Clinical university hospital	Aivars Lejnieks	300,000
Predominantly primary antibody deficiencies among adults: solving etiology and causes of clinical variability	Nataļja Kurjāne	300,000
Development of antibacterial autologous fibrin matrices in maxillofacial surgery	Arita Dubņika	90,107

2019–2023

Project	Head of project	Budget total (EUR)
Dissecting the interplay between intestinal dysbiosis and B cell function in the pathogenesis of immunoglobulin A nephropathy	Harijs Čerņevskis	299,799
Selection of biomarkers in ME/CFS for patient stratification and treatment surveillance / optimisation	Modra Murovska	300,000
Excess weight, dietary habits and vitamin D and Omega-3 fatty acid status in pregnancy	Laila Meija	300,000
Impact of Targeted Molecular Imaging with 18F-PSMA-1007 and 68Ga-PSMA-11 PET/CT in Multimodal Evaluation of Recurrent Prostate Cancer	Maija Radziņa	300,000
Memento Mori: End of Life, Death and Imagined Afterlife in the Contemporary Latvian Lifeworld	Agita Misāne	299,922

2020–2021

Project	Head of project	Budget total (EUR)
Investigating the Role of Genome Instability in Male Infertility	Juris Ērenpreiss	100,389
Pilot study: newborn screening for spinal muscular atrophy	Madara Kreile	100,389
Human herpesvirus 6 chemokine receptor mediated immunomodulating mechanism involvement in autoimmune thyroiditis development	Alīna Sultanova	100,389
Using Machine Learning To Model The Complex Interplay Between Diet, Genetic Factors and Mitochondria in Coronary Artery Disease	Baiba Vilne	100,389
Uncovering the impact of weight loss on obesity-induced changes in B cell metabolism and function	Kristīne Oļeiņika	100,389
Automated hand washing quality control and quality evaluation system with real-time feedback	Oļegs Sabeļņikovs	100,389
The role of human herpesvirus-6 infection and alcohol abuse in the development of neuroinflammation	Sandra Skuja	100,389
Multiparametric ultrasound correlation with morphology in patients with primary hyperparathyroidism	Zenons Narbuts	100,389
Biomarkers for early diagnosis of bladder tumor	Miki Nakazawa-Miklaševiča	100,389
Pathogenicity of human Hepatitis C virus relying on enzymatic properties of viral RNA-dependent RNA-polymerase	Juris Jansons	100,389

2018–2021

Project	Head of project	Budget total (EUR)
Investigation of the chemokine receptors CCR1 and CCR2 and EBV infection aimed on disclosure of new markers that can predict the high risk for progression of chronic lymphocytic leukemia	Irina Holodņuka	300,000
Interdisciplinary study of inflammatory joint disease-associated influence on neurocognitive function	Valērija Groma	299,589
Prostate cancer-derived extracellular vesicles as liquid biopsies and therapeutic targets	Aija Linē (BMC)	75,000

2018–2020

Project	Head of project	Budget total (EUR)
Diversity of intestinal microbiota under the influence of health and lifestyle associated dietary regimens	Angelika Krūmiņa (ZI BIOR)	41,554
New approach to active immunotherapy of Hepatitis C related cancer (LIVE®VAC)	Maria Issagouliantis	200,000
Interplay of Environmental and Genetic Factors in the Immunologic Mechanisms of Thyroid Autoimmune Diseases	Ilze Konrāde	199,998
Biomarkers of gut microbiome changes in children with autism spectrum disorders	Edvīns Miklaševičs	200,000
State Performance and Biosocial Relatedness (RELATE.LV)	Klāvs Sedlenieks	194,350