.
RSU Grants
2022–2023
- Assessment of new biomarkers for the prognosis and treatment prediction in chronic lymphocytic leukemia
- Benefits of an arterial hypertension therapy evaluation model combining laboratory and clinical capabilities in polypharmacy conditions
- Development of genetic testing strategies for hereditary breast and ovarian cancer risk detection by analysis of spectrum of predisposing mutations and their phenotypic manifestations
- Dissolution modelling for enhanced drug delivery systems (ModelDrug)
- Fibromyalgia associated microbiome, viral infection and immunological profile
- Gastric neuroendocrine tumours as a consequence of autoimmune disorders
- Herbal Medicine Chemical Fingerprints: Tool for Solutions (HerbPrint)
- High hydrostatic pressure /Radiation sterilisation: advanced processing method for future implantable gel-like biomaterials (SafeGel)
- Hypoxia-induced molecular alterations in triple negative breast cancer cell lines
- Identification of specific osteoarthritis phenotypes and disease endotypes tackled using the molecular and cellular assessment of the synovium-cartilage-bone interplay
- Imaging performance of multiparametric US and cross-sectional CT and MRI biomarkers using multimodal approach in the evaluation of renal masses to define standardized diagnostic algorithms
- Multimodal optical technique for fluid resuscitation and vasopressor therapy guidance in critically ill COVID-19 patients
- Occupational health and safety risks during 3D printing
- Patient safety incident reporting and learning system: ethical and legal perspective
- Pharmacogenomics of drug resistant tuberculosis
- Short- and long-term consequences of SARS-CoV-2 infection on children’s health: clinical and immunological profile of children with prolonged COVID-19 symptoms. Development of diagnostic and treatment protocols for children with acute abdominal pain durin
- The Role of Motor Reserve in Cognitive Dysfunction in Older Adults (MORE-COG)
- Willingness to Defend One’s Own Country During Inter-state Confrontation: the Case of Latvia and Ukraine During the Exacerbation in Relations with Russia in 2021 and 2022
2021–2022
- Countries’ engagement in other countries’ crises – factors that influence decision: cases of Belarus and Ukraine
- Development of screening algorithm for high breast and ovarian cancer risk by analysis of spectrum of predisposing mutations and their phenotypic manifestations
- Diagnostic accuracy of artificial intelligence systems for radiographic caries detection and high-quality dataset of annotated radiographs
- Hereditary angioedema: Research of genetic etiology
- Identification of plasma biomarkers for dynamic monitoring of chemotherapy efficacy in metastatic colorectal cancer patients
- Modifiable Bio and Life-Style Markers in Predicting Cognitive Decline
- Study on the antibacterial effect of biomaterials impregnated with baacteriophages
- 2020–2021
- Assessment of potential genetic factors in tuberculosis
- Characterisation of genetic variance induced foetal structural anomalies using deep phenotyping and genotyping
- Climate change narrative in Latvia: in search of a “golden opportunity” for civil society, the economy and foreign policy
- Complex study on the correlation of remodelling of tissues affected by the most common craniofacial anomalies in Latvia with tissue phenotype and inflammation
- Development of a gene panel for more effective diagnosis of genetic causes for male infertility
- Development of methodology for the use of organoid cultures of normal and malignant mammary tissues as a model system for the study of diagnostic extracellular vesicle biomarkers
- Discovering biomarkers of disease progression and variability in Charcot-Marie-Tooth neuropathy
- Factors and actors influencing the willingness in society to defend the state: Baltic states
- Hypoxia-related biomarkers in HER2 + breast cancer cell lines for the development of personalised therapy
- Impact of orthognathic surgery on facial skeletal and soft tissue structures
- Non-invasive diagnostic and predictive biomarkers for early diagnosis and prognosis of bladder tumours
- Phytochemical compounds in fruits of Viburnum opulus L. genotypes can improve the results of drug treatment in patients with primary arterial hypertension
- Real overall exposure to lead dust of different fractures at shooting ranges
- Serum cytokine dynamics in pulmonary tuberculosis patients
- Study of new biomarkers in calcified aortic valve stenosis
- Study of the causes of genetic ethology of preterm birth in women with istmocervical insufficiency using the next generation sequencing technology
- Study of the degree/structure of PSA, PSMA and TCERG1L DNA methylation in cancer and non-cancer cell lines
- Study on the antibacterial effect of biomaterials impregnated with baacteriophages
- To establish a sustainable media system in Latvia: from the assessment of the international risks of journalism to the improvement of media responsibility
- Use of artificial intelligence and robots in health care: legal framework and challenges
- 2019–2020
- To elaborate research project applications
- Characterization of genetic variance induced foetal structural anomalies using deep-phenotyping and genotyping
- Complex clinical, molecular biologic and microbiological study in children with non-complicated and complicated intra-abdominal infection in a wide age range
- Development of biomarkers and therapeutic drug monitoring as tool to personalize immunosuppresive therapy in kidney transplant recipients
- Development of the Center for Rare Diseases health care model in University hospital
- HLA Class II alleles, levels of cytokines, and expression level of ORAI1 and STIM1 genes in blood as predictors of sputum culture conversion status in patients with different forms of tuberculosis (TB)
- Identification of subgroups for escalating and de-escalating treatment in breast cancer by combined use of clinical-pathological and genomic tests
- Impact of PSMA Ligand PET/CT Examination in Multimodal Imaging of Recurrent Prostate Cancer PSMA
- Investigation of possibility to use fullerene nanoparticles in development of novel therapeutic agents against autoimmune thyroiditis
- Recapitulation of genomic, transcriptomic and phenotypical characteristics of primary breast tumors in spheroid and organoid 3D cultures in vitro as potential model of personalized medicine
- Research on antimicrobial bacteriophage effects against multidrug-resistant micro-organisms
- Societal resilience and psychological defense in small multhi-ethnic democracies: the case of Latvia
- Study of the effect of Oct4 DNA methylation degree/methylation patterns and the level of Oct4 isoforms expression on identification of the prostate cancer aggressiveness
- The elaboration of diagnostic prognostic factor algorithm of facial tissue complex regeneration for cleft patients in longitudinal aspect
- The Role of Genetic Variations, MicroRNA Expression and Impaired Carbohydrate Metabolism in Early Atherosclerosis Development and the Potential Role of Different Lipid Lowering Drug Therapies in the Preventions of Further Atherosclerosis Progression
- For the continuation of the state research program
- Analysis of drug-resistant M. tuberculosis strains involved in mico-outbreaks of tuberculosis
- Assessment of the efficacy of conservative treatment and the safety of research methods in patients with acute appendicitis ages 7 to 18
- Differences in biochemical and immunogenetic markers of apoptosis and fibrosis and endotoxins in patients with immunosuppressive RNA virus (HIV, HCV)-induced chronic infections and their correlation to infection severity
- Inquiry into the causes, effects and prevention options of chemical pollution: public and expert opinions
- Persistent viral infection involvement in immune system modulation and in the development of systemic autoimmune diseases.
- Personalised cancer diagnosis and determination of treatment efficiency
- Study of life-threatening infections in children by improving early diagnosis using modern diagnostic methods, developing and introducing new action algorithms that are compatible with the healthcare system in Latvia
- The effects of long-term physical activity on the burden caused by cognitive dysfunction and depression in elderly people
- 2013–2016
- Assessment of the activity of mitochondria-targeted substances and their compounds in the ex vivo model of mitochondrial damage
- Association of skeletal and soft tissue dismorphism of facial jaw deformations with stability of treatment outcomes
- Characteristics of B. afzelii surface proteins and development of Latvian-specific diagnostic markers of Lyme borreliosis
- Clinical features of the infection caused by rotavirus, molecular epidemiology in hospitalised children and associated quality of life of the child and family
- Epidemiology, pathogenicity and potential association of human bocavirus (HBoV) types with diseases of deep airways and acute gastroenteritis in children
- Human papillomavirus infection in kidney transplant patients
- Longitudinal study of cleft morphopathogenesis
- Overcoming the crisis in Latvia: economic, social and communication aspects
- Reconstruction of genetic evolution of breast cancer based on the cancer cell culture proteomics
- Research of clinical and molecular characteristics of cervical cancer research to improve the early diagnostics and treatment strategy
- Role of oxidative stress and discoagulation in development of acute respiratory distress syndrome
- The association of fibromyalgia and myalgic encephalomyelitis/chronic fatigue syndrome associated with beta-herpesviruses (HHV-6A, HHV-6B, HHV-7) and parvovirus B19 infection
- The association of human heart valve abnormalities with parvovirus B19 and herpesvirus HHV-6 infection – morphological, virological and biomechanical aspects
- The molecular and radiological profile of thyroid cancer for improvement of early and substantiated diagnostics
