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Colistin is a kidney-damaging (nephrotoxic) antibacterial agent. It is currently used in several countries, including Latvia, for critically ill patients due to the spread of multidrug-resistant Gram-negative (Gr-) bacterial infections. Unfortunately, there are currently limited alternatives treating these severe infections. Therefore, special attention should be paid to the proper use of available agents, which includes correct dosing, to minimise the potential development of colistin resistance.

Research on the effect of phages in treating bacterial infections

Nowadays, multidrug-resistant bacterial infections are on the rise, which means that treatment with antibiotics may not be effective. Bacteriophage therapy is an alternative treatment for bacterial infections.

Bacteriophages or phages are bacterial viruses that enter bacteria, then replicate and kill them. This principle can be used to treat bacterial infections when antibiotics do not have the desired effect.

New autoimmunity centre opens at Riga East Clinical University Hospital

On 6 December, a celebratory opening of the new Autoimmunity Centre was held at the Riga East Clinical University Hospital (Rīgas Austrumu klīniskā universitātes slimnīca, RAKUS). The centre aims to conduct in-depth scientific research on autoimmune diseases and promote the hospital’s doctors and residents’ involvement in scientific research activities, as well as international collaboration.

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Right ventricular failure causes significant limitation of physical activity and impaired quality of life in patients and is a cause of premature death. Treatment options for right ventricular failure are very limited worldwide. It is therefore essential to study and explore new medications and molecules that could potentially improve the function of the right ventricle, and consequently patients’ quality of life and survival rate.

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